Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone HMB45] (IgG1,k) to Human Melanoma
IHC, Western blot
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [HMB45]
Tissue culture supernatant
Western blot (1:50 - 1:100)
Specificity and Use
Melanoma antibody was raised against bALB/C mice were injected with extract of pigmented melanoma metastases from lymph nodes.
Reacts with a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. It reacts with junctional and blue nevus cells. Non-melanocytic cells are negative.