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Anti-MDM4 / MDMX Antibody (clone 2C1) LS-C174500
Most Popular MDM4 / MDMX Antibodies
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Details
| Human MDM4 / MDMX | |
| Mouse | |
| Human (tested or 100% immunogen sequence identity) | |
| IgG1 Monoclonal [2C1] | |
| Unconjugated | |
| Protein A/G purified | |
| Unmodified |
Applications
- IHC
- IHC - Paraffin (1:150)
- Immunofluorescence (1:100)
- Western blot (1:2000)
Specificity and Use
| MDM4 / MDMX antibody was raised against full length human recombinant protein of human MDM4(NP_002384) produced in HEK293T cell. | |
| Human MDM4 / MDMX |
Packaging
| PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide | |
| Store at -20°C. Avoid freeze-thaw cycles. | |
| For research use only. |
About MDM4 / MDMX
O15151
NM_002393
NP_002384.2
MDM4 Antibody, Mdm2-like p53-binding protein Antibody, MDMX Antibody, HDMX Antibody, MRP1 Antibody, p53-binding protein Mdm4 Antibody, Protein Mdm4 Antibody, Double minute 4 protein Antibody, MDM4-related protein 1 Antibody, Protein Mdmx Antibody
MDM4 / MDMX is a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.
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Requested From:
Date Requested: 4/26/2018
Date Requested: 4/26/2018
