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Anti-MDM4 / MDMX Antibody (aa336-385) LS-C199242

Ordering

Wt. Vol. Conc. Price
- 20 µl - $205
- 50 µl - $255
- 100 µl - $315
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MDM4 / MDMX Antibodies

Anti-MDM4 / MDMX Antibody (clone 2C1) LS-C174500
Mouse Monoclonal [clone 2C1] (IgG1) to Human MDM4 / MDMX
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-MDM4 / MDMX Antibody (clone 3B9) IHC-plus™ LS-B13608
Mouse Monoclonal [clone 3B9] (IgG2b) to Human MDM4 / MDMX
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry - Paraffin Image
Anti-MDM4 / MDMX Antibody (clone 4G3) IHC-plus™ LS-B13609
Mouse Monoclonal [clone 4G3] (IgG2b) to Human MDM4 / MDMX
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human MDM4 / MDMX
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human MDM4 / MDMX
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot
  • ELISA

Specificity and Use

MDM4 / MDMX antibody was raised against synthetic peptide from human MDM4 (aa336-385).
aa336-385
MDM4 (Ab-367) Antibody detects endogenous levels of total MDM4 protein.

Packaging

PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Store at -20°C.
For research use only.

About MDM4 / MDMX

O15151 NM_002393 NP_002384.2

MDM4 Antibody, Mdm2-like p53-binding protein Antibody, MDMX Antibody, HDMX Antibody, MRP1 Antibody, p53-binding protein Mdm4 Antibody, Protein Mdm4 Antibody, Double minute 4 protein Antibody, MDM4-related protein 1 Antibody, Protein Mdmx Antibody

MDM4 / MDMX is a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.

Immunohistochemistry

Immunohistochemistry
IHC of paraffin-embedded human colon carcinoma tissue, using MDM4 Antibody. The sample on the right was incubated with synthetic peptide.

Western blot

Western blot
Western blot of extracts from rat muscle cells, using MDM4 Antibody. The lane on the right was incubated with synthetic peptide.

Requested From: United States
Date Requested: 12/6/2016

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