LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
MCM2 Antibody (clone CRCT2.1 (D1.9H5)) LS‑C11595
MCM2 antibody LS-C11595 is an unconjugated mouse monoclonal antibody to human MCM2. Validated for IHC and WB.
Catalog
Size
Price
LS-C11595-100
100 µg (1 mg/ml)
$405

Popular MCM2 Products

Anti-MCM2 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B391 concentration 5 ug/ml.
Species: Human, Mouse, Rat, Yeast
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Detection of Human Phospho MCM2 (Ser 41) by Immunohistochemistry. Samples: FFPE serial sections of human colon carcinoma. Mock phosphatase treated section (left) or CIP phosphatase-treated section (right). Antibody: Affinity purified rabbit anti-Phospho MCM2 (Ser 41) used at a dilution of 1:250. Detection: DAB staining using anti-Rabbit IHC antibody 1:100.
Species: Human, Mouse, Rat, Bovine, Dog, Horse, Rabbit, Xenopus
Applications: IHC, IHC - Paraffin, Immunofluorescence
IHC of paraffin-embedded ovarian cancer tissues using MCM2 mouse monoclonal antibody with DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Detection of Human and Mouse MCM2 (S53) Immunohistochemistry. Sample: FFPE sections of human breast carcinoma (left) and mouse renal cell carcinoma (right). Antibody: Affinity purified rabbit anti-MCM2 (S53) No. Lot4) used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Proximity Ligation Assay
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence

Product Description

MCM2 antibody LS-C11595 is an unconjugated mouse monoclonal antibody to human MCM2. Validated for IHC and WB.
About MCM2
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. P49736 NM_004526 NP_004517.2

MCM2 Antibody, BM28 Antibody, Cell devision cycle-like 1 Antibody, D3S3194 Antibody, Cdc19 Antibody, Cyclin-like 1 Antibody, KIAA0030 Antibody, Nuclear protein BM28 Antibody, CDCL1 Antibody, MITOTIN Antibody


Specifications

Target
Human MCM2
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [CRCT2.1 (D1.9H5)]
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:200)
  • IHC - Frozen (1:500 - 1:1000)
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MCM2 antibody was raised against bacterially expressed human Mcm2.
Specificity
Recognizes human DNA replication licensing factor MCM2, also known as Mcm2, Nuclear protein BM28 or mini chromosome maintenance protein-2. Mcm-2 is a 904 amino acid ~125kD nuclear protein involved in the control of DNA replication. Has been used successfully for the detection of human MCM2 in ovarian adenocarcinoma by immunohistochemistry on formalin fixed, paraffin embedded tissues.
Usage
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections 0.01 M citrate buffer pH6 is recommended for this purpose.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images

Immunohistochemistry

Paraffin-embedded human tonsil stained with Mouse anti-Human MCM2 (LS-C11595) following citrate antigen retrieval.
Paraffin-embedded human tonsil stained with Mouse anti-Human MCM2 (LS-C11595) following citrate antigen retrieval.

Immunohistochemistry

Paraffin-embedded human tonsil stained with Mouse anti-Human MCM2 (LS-C11595) following citrate antigen retrieval.
Paraffin-embedded human tonsil stained with Mouse anti-Human MCM2 (LS-C11595) following citrate antigen retrieval.

Immunohistochemistry

Paraffin-embedded human tonsil stained with Mouse anti-Human MCM2 (LS-C11595) following citrate antigen retrieval.
Paraffin-embedded human tonsil stained with Mouse anti-Human MCM2 (LS-C11595) following citrate antigen retrieval.

Immunohistochemistry

Paraffin-embedded human tonsil stained with Mouse anti-Human MCM2 (LS-C11595) following citrate antigen retrieval.
Paraffin-embedded human tonsil stained with Mouse anti-Human MCM2 (LS-C11595) following citrate antigen retrieval.

Requested From: United States
Date Requested: 8/18/2018

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy