Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human MBL2 / Mannose Binding Protein
IHC, ICC, Immunofluorescence, Western blot, ELISA
Rat Monoclonal [clone 16A8] (IgG2a) to Mouse MBL2 / Mannose Binding Protein
Mouse MBL2 / Mannose Binding Protein
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [16A8]
Specificity and Use
Purified MBL-C emulsified in complete Freund's adjuvant
Mouse MBL-C / Mannose Binding Lectin C
For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. It is recommended that solutions with a calcium concentration of 1 mM are used (16A8 is a calcium-dependent antibody).
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.