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Anti-MARCKS Antibody LS-C49163


Wt. Vol. Conc. Price
- 100 µl - $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular MARCKS Antibodies

Anti-MARCKS Antibody (C-Terminus) LS-C25423
Mouse Monoclonal (IgG1) to Human MARCKS
Human, Bovine
Western blot, Immunoprecipitation, ELISA
Anti-MARCKS Antibody (phospho-Ser158) LS-C130650
Rabbit Polyclonal (IgG) to Human MARCKS
Human, Mouse, Rat
Western blot
Anti-MARCKS Antibody (clone 2C2) IHC-plus™ LS-B5450
Mouse Monoclonal [clone 2C2] (IgG1,k) to Human MARCKS
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Rat MARCKS
IHC, ICC, Immunofluorescence, Western blot


Rat (tested or 100% immunogen sequence identity)


  • IHC (1:5000)
  • ICC (1:5000)
  • Immunofluorescence (1:500 - 1:1000)
  • Western blot (1:20000)

Specificity and Use

MARCKS antibody was raised against this antibody was made against full length recombinant MARCKS expressed in and purified from E. coli
The MARCKS protein runs at about 80kD on SDS-PAGE gels, although the real molecular is much lower, at about 31.5kD. The reason for this is probably because the protein is extremely rich in acidic residues. Such proteins appear to bind less SDS than the average protein, and so migrate in PAGE more slowly than the normal protein. MARCKS is a major protein of brain, and is concentrated in synapses of neurons. It appears to function in synaptic vesicle cycling and has been shown to bind both actin and calmodulin in vitro. MARCKS belongs to a family of proteins with similar actin and calmodulin binding properties. Deletion of the MARCKS gene in mice results in embryonic brain defects and death.


Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.


P29966 NM_002356 NP_002347.5

MARCKS Antibody, 80K-L Antibody, 80K-L protein Antibody, MACS Antibody, MRACKS Antibody, Phosphomyristin Antibody, PKCSL Antibody, PRKCSL Antibody

MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Western blot

Western blot
Western Blot: MARCKS Antibody - Western blot of whole rat cortex (Co), cerebellum (Ce), brain stem (BS) and spinal cord (SC) homogenate stained with RPCA-MARCKS, at dilution of 1:10,000. A prominent band running with an apparent SDS-PAGE molecular weight

Requested From: United States
Date Requested: 10/23/2016

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