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MAP3K15 / ASK3 is a member of the mitogen-activated protein kinase (MAPK) family. These family members function in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. This MAP3K protein plays an essential role in apoptotic cell death triggered by cellular stresses.
Gene Name: | mitogen-activated protein kinase kinase kinase 15 |
Family/Subfamily: | Protein Kinase , MAP3K |
Synonyms: | MAP3K15, ASK3, BA723P2.3, MAPK/ERK kinase kinase 15, MEK kinase 15, MEKK 15 |
Target Sequences: | SK681D SK681P Q6ZN16 |
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