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Anti-MAP3K1 / MEKK1 Antibody (aa1145-1176) LS-C99472

Catalog Size Price
LS-C99472-400 400 µl Unavailable

Related Products

49 MAP3K1 / MEKK1 Antibodies

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Anti-MAP3K1 / MEKK1 Antibody (aa1251-1300) LS-C81277
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Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken
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Anti-MAP3K1 / MEKK1 Antibody (phospho-Thr1400) LS-C97028
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Anti-MAP3K1 / MEKK1 Antibody (aa1418-1432) LS-C313059
Rabbit Polyclonal (IgG) to Human MAP3K1 / MEKK1
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Anti-MAP3K1 / MEKK1 Antibody (aa1211-1310, clone 2F6, Ready-to-Use) LS-C390619
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Anti-MAP3K1 / MEKK1 Antibody (aa1251-1300, HRP) LS-C451482
Rabbit Polyclonal (IgG) to Human MAP3K1 / MEKK1
Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken
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100% Guaranteed
Rabbit Polyclonal to Human MAP3K1 / MEKK1
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human MAP3K1 / MEKK1
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

LS-E9362 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C99472. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa1145-1176
This MEKK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1145-1176 amino acids from the C-terminal region of human MEKK1.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About MAP3K1 / MEKK1

Q13233 SK221D SK221P

MAP3K1 Antibody, MAPK/ERK kinase kinase 1 Antibody, MAPKKK1 Antibody, MAP/ERK kinase kinase 1 Antibody, MEK kinase 1 Antibody, MEKK Antibody, MEKK 1 Antibody, MEKK1 Antibody, SRXY6 Antibody

MEKK1, a MAP3K type protein kinase, is a member of the stress-activated protein kinase (SAPK) pathways which convey pro-apoptotic signals. The protein consists of a C-terminal protein kinase domain and an extensive N-terminal domain that includes two proline-rich segments containing putative binding sites for proteins with SH3 domains, a consensus binding site for 14-3-3 proteins, two PH domains and an acid rich motif with two sites for cleavage by proapoptotic caspase cysteine proteases.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
Western blot of anti-MEKK1 antibody in HL-60 cell lysate. MEKK1 (Arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Requested From: 
Date Requested: 8/16/2017

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