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Anti-Mannose Receptor / CD206 Antibody (aa19-1383, clone 685645) LS-C150006

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $315
Inquire for larger quantities

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Most Popular Mannose Receptor / CD206 Antibodies

Anti-Mannose Receptor / CD206 Antibody (clone 5C11) IHC-plus™ LS-B5474
Mouse Monoclonal [clone 5C11] (IgG1,k) to Human Mannose Receptor / CD206
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-Mannose Receptor / CD206 Antibody (aa359-388) IHC-plus™ LS-B9805
Rabbit Polyclonal to Human Mannose Receptor / CD206
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (1)
Mouse Monoclonal [clone 685645] (IgG2b) to Human Mannose Receptor / CD206
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human Mannose Receptor / CD206
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [685645]
Unconjugated
Protein A/G purified
Unmodified

Applications

  • IHC - Paraffin (8 - 25 µg/ml)
  • Western blot (1 µg/ml)

Specificity and Use

Mannose Receptor / CD206 antibody was raised against mouse myeloma cell line NS0-derived recombinant human MMR/CD206 Leu19-Lys1383 (Thr399-Ala) & (Leu407-Phe), Accession # P22897.
aa19-1383
Detects human MMR/CD206 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) MMR or.

Packaging

Lyophilized from 0.2 µm filtered PBS, pH 7.4, 5% trehalose
200ul sterile PBS
Long term: -70°C; Short term: -20°C
For research use only.

Publications (1)

1
CNS, lung, and lymph node involvement in Gaucher disease type 3 after 11 years of therapy: clinical, histopathologic, and biochemical findings. Burrow TA, Sun Y, Prada CE, Bailey L, Zhang W, Brewer A, Wu SW, Setchell KD, Witte D, Cohen MB, Grabowski GA. Molecular genetics and metabolism. 2015 Feb;114:233-41. [Full Text Article] [PubMed:25219293] [PMC:PMC4312736]

About Mannose Receptor / CD206

P22897 NM_002438 NP_002429.1

MRC1 Antibody, BA541I19.1 Antibody, CLEC13D Antibody, CD206 Antibody, CD206 antigen Antibody, Macrophage mannose receptor 1 Antibody, Mannose Receptor Antibody, Macrophage mannose receptor Antibody, MMR Antibody, Mannose receptor, C type 1 Antibody, MRC1L1 Antibody, CLEC13DL Antibody

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages.

Immunohistochemistry

Immunohistochemistry
MMR/CD206 in Human Liver. MMR/CD206 was detected in immersion fixed paraffin-embedded sections of human liver using Mouse Anti-Human MMR/CD206 Monoclonal Antibody at 15 ug/ml overnight at 4°C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic. Tissue was stained using Anti-Mouse HRP-DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to endothelial cells in caniculi.

Western blot

Western blot
Detection of Human MMR/CD206 by Western Blot. Western blot shows lysates of human immature dendritic cells. PVDF Membrane was probed with 1 ug/ml of Mouse Anti-Human MMR/CD206 Monoclonal Antibody followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody. A specific band was detected for MMR/CD206 at approximately 150 kD (as indicated). This experiment was conducted under reducing conditions.

Requested From: United States
Date Requested: 12/3/2016

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