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MAML1

mastermind-like 1 (Drosophila)

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.

Gene Name: mastermind-like 1 (Drosophila)
Synonyms: MAML1, Mam1, Mastermind homolog, Mastermind-like protein 1, Mastermind (drosophila)-like 1, Mastermind-like 1 (Drosophila), KIAA0200, Mam-1
Target Sequences: NM_014757 NP_055572.1 Q92585

☰ Filters
Antibodies (18)
Proteins (4)
Over-Expression Lysate (2)
Primary (18)
Recombinant (2)
MAML1 (22)
Human (18)
Mouse (1)
Monkey (1)
Pig (1)
Rodent (1)
IHC (6)
IHC-Fr (1)
IHC-P (3)
WB (13)
Flo (7)
ELISA (12)
IP (3)
Peptide-ELISA (1)
rabbit (17)
goat (1)
Product Group
IHCPlus (1)
IgG (16)
polyclonal pc (18)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (10)
aa198-225 (7)
aa75-125 (2)
aa1-50 (1)
aa1000-C-term (1)
aa2-15 (1)
aa661-676 (1)
No (22)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
MAML1 Antibody - Anti-MAML1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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MAML1 Goat anti-Human Polyclonal (aa2-15) Antibody
Mouse, Pig, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Select
MAML1 Rabbit anti-Human Polyclonal (aa661-676) Antibody
Rodent, Human
ELISA, IHC, IHC-Fr, WB
Unconjugated
50 µg/$538
MAML1 Antibody - Detection of Human MAML1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-MAML1 used at a dilution of 1:200 (1 Detection: DAB.
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MAML1 Rabbit anti-Human Polyclonal (aa1000-C-term) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
MAML1 Rabbit anti-Human Polyclonal (aa198-225) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
Select
MAML1 Rabbit anti-Human Polyclonal (aa198-225) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
Select
MAML1 Rabbit anti-Human Polyclonal (aa198-225) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
Select
MAML1 Rabbit anti-Human Polyclonal (aa198-225) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
Select
MAML1 Rabbit anti-Human Polyclonal (aa198-225) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
Select
MAML1 Rabbit anti-Human Polyclonal (aa198-225) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
MAML1 Antibody - Detection of Human MAML1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-MAML1 used at a dilution of 1:1000 (1 Detection: DAB.
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MAML1 Rabbit anti-Human Polyclonal (aa75-125) Antibody
Human
IHC, IP, WB
Unconjugated
100 µl/$514
MAML1 Antibody - Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution of 1:100
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MAML1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
MAML1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
MAML1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
MAML1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
MAML1 Antibody - MAML1 Antibody western blot of 293,NCI-H460 cell line lysates (35 ug/lane). The MAML1 antibody detected the MAML1 protein (arrow).
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MAML1 Rabbit anti-Human Polyclonal (aa198-225) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
Select
MAML1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
MAML1 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IP, WB
Unconjugated
100 µl/$456
MAML1 Antibody - Detection of Human MAML1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-MAML1 used at a dilution of 1:250.
Select
MAML1 Rabbit anti-Human Polyclonal (aa75-125) Antibody
Human
IHC
Unconjugated
2.5 µg/$295; 100 µl/$532
MAML1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
107.9 kDa
100 µg/$710
MAML1 Protein - Purified recombinant protein MAML1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
107.9 kDa
20 µg/$1,107
MAML1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MAML1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
107.9 kDa
20 µg/$215
Viewing 1-22 of 22 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).