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MAGEB3 is a MAGE-B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE-A subfamily are located in the Xq28 region, while the members of the MAGE-B subfamily are clustered in the Xp21 region.
Gene Name: | melanoma antigen family B, 3 |
Synonyms: | MAGEB3, CT3.5, MAGE-B3 antigen, Melanoma-associated antigen B3, Melanoma antigen family B, 3 |
Target Sequences: | NM_002365 NP_002356.2 O15480 |
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