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Anti-MAGEA2 Antibody (aa96-108) IHC-plus™ LS-B883

Note: This antibody replaces LS-C3100

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MAGEA2 Antibodies

Anti-MAGEA2 Antibody (aa96-108) IHC-plus™ LS-B883
Rabbit Polyclonal to Human MAGEA2
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MAGEA2 Antibody (N-Terminus, APC) LS-C279069
Rabbit Polyclonal (IgG) to Human MAGEA2
Human
IHC, Western blot, ELISA
APC Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human MAGEA2
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human MAGEA2
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • ELISA (1:1000)

Specificity and Use

MAGEA2 antibody was raised against synthetic peptide from human MAGEA2.
aa96-108
Amino acids 96 to 108 of human MAGEA2
Immunohistochemistry: LS-B883 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B883 was determined to be 5 ug/ml.

Packaging

PBS, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About MAGEA2

P43356 NM_005361 NP_005352.1

MAGEA2 Antibody, Cancer/testis antigen 1.2 Antibody, MAGE-2 antigen Antibody, MAGEA2A Antibody, Melanoma antigen 2 Antibody, Melanoma antigen family A, 2 Antibody, MAGE2 Antibody, CT1.2 Antibody, Melanoma-associated antigen 2 Antibody

Reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites. Also represses p73/TP73 activity. Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination by TRIM28 potentially in presence of Ubl-conjugating enzyme UBE2H.

Immunohistochemistry

Immunohistochemistry
Anti-MAGEA2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B883 concentration 5 ug/ml.
 

Requested From: United States
Date Requested: 12/11/2016

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