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Anti-Macrophage Antibody (clone MOMA-1, Biotin) LS-C96367

Ordering

Wt. Vol. Conc. Price
200 µg - - $590
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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Rat Monoclonal [clone MOMA-1]
Mouse
IHC - Frozen
Biotin Conjugated

Details

Macrophage
Rat
Mouse (tested or 100% immunogen sequence identity)
Monoclonal [MOMA-1]
Biotin
Affinity purified
Unmodified

Applications

IHC - Frozen (1:400 - 1:800)

Specificity and Use

Macrophage antibody was raised against lymph node
The antigen is found intracellularly and on cell surface on metallophilic macrophages. Antigen distribution: Isolated cells: No reactivity of MOMA-1 was found with dendritic cells, peritoneal resident macrophages, peritoneal exudate cells, bone marrow or blood cells. Tissue sections: Distinct macrophage subpopulations of lymphoid organs express the antigen. In the spleen, they are localized at the marginal sinus forming a ring around the periarteriolar lymphocyte sheath and follicular areas at the inner side of marginal zones. In lymph nodes, they are localized in the sinusoids and medullary cords, but not within follicular areas or paracortex. In Peyer's patches they are localized in the interfollicular areas at the serosal side. Kupffer cells in the liver can be clearly stained by MOMA-1. No MOMA- 1-positive macrophages were found in the thymus, brain, kidney, liver, skin or heart. In non-lymphoid organs, the antigen is only found on a macrophage subpopulation in the lamina propria of the villi of the small intestine. Specificity: Mouse: Subpopulation of mature resident tissue macrophages. Other species: not tested.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized from PBS pH 7.2, 5mg/ml BSA, 0.05% Kathon
0.5ml distilled water
Store at 4°C.
For research use only.

About Macrophage

Macrophages (Greek: big eaters, from makros "large" + phagein "eat"; abbr. MF), are a type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, cancer cells, and anything else that does not have the types of proteins specific to the surface of healthy body cells on its surface in a process called phagocytosis. Macrophages were first discovered by Élie Metchnikoff, a Russian bacteriologist, in 1884.

Requested From: United States
Date Requested: 12/7/2016

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