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Anti-Macrophage Antibody (clone 25F9, Biotin) LS-C96221

Ordering

Wt. Vol. Conc. Price
200 µg - - $590
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 25F9]
Human
IHC - Paraffin
Biotin Conjugated

Details

Macrophage
Mouse
Human (tested or 100% immunogen sequence identity)
Monoclonal [25F9]
Biotin
Affinity purified
Unmodified

Applications

IHC - Paraffin (1:200)

Specificity and Use

Macrophage antibody was raised against cultured human monocytes
The antigen is a 86kDa membrane protein, the epitope has not been further characterized. Antigen distribution: Isolated cells: Absent on freshly isolated monocytes and other blood cells; present on 40 - 50% of human monocytes after 6-7 days in culture, also positive on some melanoma and carcinoma cell lines. Tissue sections: Kupffer cells, histiocytes (skin), macrophages of the thymus, in the germinal centres of lymph nodes and spleen, in mamma carcinoma, melanoma, osteocarcinoma and gastric cancer; eczema, sarcoidosis, BCG granuloma; synovial lining cells, tuberculoid leprosy: no expression in lepromatous leprosy. Specificity: Human: mature macrophages and monocytes. Other: subpopulation of macrophages in Rhesus monkey; reactive with pig alveolar macrophages and Kupffer cells.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
0.5ml distilled water
Store at 4°C.
For research use only.

About Macrophage

Macrophages (Greek: big eaters, from makros "large" + phagein "eat"; abbr. MF), are a type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, cancer cells, and anything else that does not have the types of proteins specific to the surface of healthy body cells on its surface in a process called phagocytosis. Macrophages were first discovered by Élie Metchnikoff, a Russian bacteriologist, in 1884.

Requested From: United States
Date Requested: 12/3/2016

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