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Human M6PR | |
Goat | |
Human, Monkey, Mouse, Rat, Bat, Horse, Pig (tested or 100% immunogen sequence identity) | |
Bovine, Dog, Rabbit (at least 90% immunogen sequence identity) | |
Polyclonal | |
Unconjugated | |
Immunoaffinity purified | |
Unmodified |
ELISA (1:4000) |
IHC - Paraffin |
M6PR antibody was raised against synthetic peptide KGGDEYDNHCGKEQ from an internal region of human M6PR (NP_002346.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Bat, Horse, Pig, Opossum (100%); Panda, Dog, Bovine, Rabbit (93%). | ||
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aa123-136 | ||
Human M6PR. |
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide | |
Store at -20°C. Avoid freeze-thaw cycles. | |
For research use only. |
M6PR Antibody, CD-MPR Antibody, SMPR Antibody, MPR46 Antibody, MPRD Antibody, Mr 46,000 Man6PR Antibody, CD Man-6-P receptor Antibody, MPR 46 Antibody, MPR-46 Antibody
Targeting of newly synthesized lysosomal enzymes in many cell types depends on formation of mannose 6-phosphate residues on lysosomal enzymes and recognition of these residues by specific receptors. The cation-dependent mannose 6-phosphate receptor is one of the two transmembrane proteins involved in transport of lysosomal enzymes. Binding of ligands to this receptor is dependent on divalent cations and pH.