Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Syrian hamster Monoclonal [clone 14B11] (IgG) to Mouse Ly49C+F+H+I
Hamster Monoclonal [clone 14B11] (IgG) to Mouse Ly49C+F+H+I
Mouse (tested or 100% immunogen sequence identity)
IgG Monoclonal [14B11]
Specificity and Use
Ly49C+F+H+I antibody was raised against mouse Ly49C/Ly49F/Ly49H/Ly49I
The 14B11 antibody has been tested by flow cytometric analysis of mouse splenocyte suspensions. This can be used at less than or equal to 0.125 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, pH 7.2, 150 mM sodium chloride, 0.09% sodium azide
Staining of C57Bl/6 splenocytes with FITC anti-mouse CD49b/DX5 and 0.125 ug of PE 14B11. Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of C57Bl/6 splenocytes with FITC anti-mouse CD49b/DX5 and staining buffer (autofluorescence). Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.