![]() |
|
|
|
|||||||||||
|
|||||||||||
|
|||||||||||
|
|||||||||||
|
![]() |
|
Mouse LTBR | |
Rat | |
Mouse (tested or 100% immunogen sequence identity) | |
IgG2a Monoclonal [5G11b] | |
Unconjugated. Also available conjugated with Biotin, FITC, RPE. | |
Protein G purified | |
Unmodified. Also available Low Endotoxin. |
LTBR antibody was raised against recombinant extracellular domain of LT beta R. | |
Extracellular Domain | |
Recognizes murine lymphotoxin-beta receptor (LT beta R), a member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognizes surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release. This product is routinely tested on WEH1 cells. |
PBS, 0.09% sodium azide | |
+4°C or -20°C, Avoid repeated freezing and thawing. | |
For research use only. |
LTBR Antibody, D12S370 Antibody, CD18 Antibody, LT-BETA-R Antibody, Lymphotoxin B receptor Antibody, Lymphotoxin-beta receptor Antibody, TNFR3 Antibody, TNF-R-III Antibody, TNF-RIII Antibody, TNFCR Antibody, TNFRSF3 Antibody, TNFR-III Antibody, TNFR-RP Antibody, TNFR2-RP Antibody
LTBR is a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis.