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LTBR Antibody (Extracellular Domain, clone 5G11b) LS‑C188249
LTBR antibody LS-C188249 is an unconjugated rat monoclonal antibody to mouse LTBR. Validated for Flow.
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Species:
Human
Applications:
Western blot, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
Flow Cytometry, ELISA
Species:
Mouse
Applications:
Flow Cytometry, Functional Assay
Product Description
LTBR antibody LS-C188249 is an unconjugated rat monoclonal antibody to mouse LTBR. Validated for Flow.
About LTBR
LTBR is a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis.
P36941
NM_002342
NP_002333.1
LTBR Antibody, D12S370 Antibody, CD18 Antibody, LT-BETA-R Antibody, Lymphotoxin B receptor Antibody, Lymphotoxin-beta receptor Antibody, TNFR3 Antibody, TNF-R-III Antibody, TNF-RIII Antibody, TNFCR Antibody, TNFRSF3 Antibody, TNFR-III Antibody, TNFR-RP Antibody, TNFR2-RP Antibody
Specifications
Target
Mouse LTBR
Host
Rat
Reactivity
Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG2a
Monoclonal
[5G11b]
Purification
Protein G purified
Modifications
Unmodified.
Also available Low Endotoxin.
Applications
- Flow Cytometry (1:50 - 1:100)
- (applications tested for the base form of this product only)
Immunogen
LTBR antibody was raised against recombinant extracellular domain of LT beta R.
Epitope
Extracellular Domain
Specificity
Recognizes murine lymphotoxin-beta receptor (LT beta R), a member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognizes surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release. This product is routinely tested on WEH1 cells.
Presentation
PBS, 0.09% sodium azide
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
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Requested From:
Date Requested: 6/18/2018
Date Requested: 6/18/2018
