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Anti-LTBR Antibody (Extracellular Domain, clone 5G11b) LS-C188249

Catalog	Size	Price
LS-C188249-100	100 µg (1 mg/ml)	Unavailable

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Anti-LTBR Antibody (Extracellular Domain, clone 5G11b, Low Endotoxin) LS-C188247

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Anti-LTBR Antibody (aa420-435) LS-C313101

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Application:	IHC - Paraffin, Western blot
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Antibody:	Rat Monoclonal [clone 5G11b] (IgG2a) to Mouse LTBR
Reactivity:	Mouse
Application:	Flow Cytometry (applications tested for the base form of this product only)
Format:	Unconjugated

Details

Target:	Mouse LTBR
Host:	Rat
Reactivity:	Mouse (tested or 100% immunogen sequence identity)
Clonality:	IgG2a Monoclonal [5G11b]
Conjugations:	Unconjugated. Also available conjugated with Biotin, FITC, RPE.
Purification:	Protein G purified
Modifications:	Unmodified. Also available Low Endotoxin.

Applications

Approved:

Flow Cytometry (1:50 - 1:100)
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:	LTBR antibody was raised against recombinant extracellular domain of LT beta R.
Epitope:	Extracellular Domain
Specificity:	Recognizes murine lymphotoxin-beta receptor (LT beta R), a member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognizes surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release. This product is routinely tested on WEH1 cells.

Packaging

Presentation:	PBS, 0.09% sodium azide
Storage:	+4°C or -20°C, Avoid repeated freezing and thawing.
Restrictions:	For research use only.

About LTBR

Uniprot: P36941 NCBI: NM_002342 NP_002333.1

Synonyms: LTBR Antibody, D12S370 Antibody, CD18 Antibody, LT-BETA-R Antibody, Lymphotoxin B receptor Antibody, Lymphotoxin-beta receptor Antibody, TNFR3 Antibody, TNF-R-III Antibody, TNF-RIII Antibody, TNFCR Antibody, TNFRSF3 Antibody, TNFR-III Antibody, TNFR-RP Antibody, TNFR2-RP Antibody

Description: LTBR is a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis.

(More About LTBR)

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Date Requested: 6/23/2017

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