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Anti-LRRC8A / LRRC8 Antibody (N-Terminus) LS-C81385

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular LRRC8A / LRRC8 Antibodies

Anti-LRRC8A / LRRC8 Antibody (aa648-803) LS-C179163
Rabbit Polyclonal to Human LRRC8A / LRRC8
Human
IHC, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-LRRC8A / LRRC8 Antibody (aa782-810, APC) LS-C262260
Rabbit Polyclonal (IgG) to Human LRRC8A / LRRC8
Human
Western blot, ELISA
APC Conjugated
Anti-LRRC8A / LRRC8 Antibody (N-Terminus) IHC-plus™ LS-B13087
Rabbit Polyclonal (IgG) to Human LRRC8A / LRRC8
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human LRRC8A / LRRC8
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human LRRC8A / LRRC8
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

LRRC8A / LRRC8 antibody was raised against synthetic peptide from N-Terminus of human LRRC8A (Q8IWT6, NP_062540). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Galago, Marmoset, Mouse, Rat, Shrew, Hamster, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Armadillo, Platypus, Xenopus, Zebrafish (100%).
N-Terminus
Human LRRC8A
ELISA titer using peptide based assay: 1:62500. Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.

Packaging

Lyophilized from PBS with 2% sucrose
50 µl Distilled Water.
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About LRRC8A / LRRC8

Q8IWT6 AB037858 BAA92675.1

LRRC8A Antibody, AGM5 Antibody, LRRC8 Antibody, KIAA1437 Antibody

Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8A constitutes a pore-forming subunit or whether it is closely associated with the pore and mediates channel properties such as ion selectivity.

Western blot

Western blot
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/5/2016

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