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Anti-LRP5 Antibody (C-Terminus) LS-C8514


Wt. Vol. Conc. Price
50 µg 200 µl - Unavailable
100 µg - - Unavailable

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100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human LRP5
Human, Mouse
Immunofluorescence, Western blot


Human LRP5
Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • Immunofluorescence (2 - 3 µg/ml)
  • Western blot (1 - 3 µg/ml)

Specificity and Use

LRP5 antibody was raised against synthetic peptide derived from the C-terminal region of the human LRP5 protein. This intracellular region is identical to the corresponding mouse and rat LRP5 amino acid sequences.
Recognizes human LRP5 protein. Western Blot tests using negative control mock pSEC-tag-transfected 293T cell lysates did not yield the target band. Species cross-reactivity: Mouse.
Suitable for use in Immunofluorescence and Western Blot. Immunofluorescence: 2-3 ug/ml; Note: For optimal results in immunofluorescence assays, cells should be fixed in 4% paraformaldehyde/0.5% Triton X-100/PBS for 10 minutes, permeabilized with 0.5% Triton X-100/PBS for 5 minutes, and blocked with 5% BSA/PBS for 30 minutes. Western Blot: 1-3 ug/ml; Single band at ~200kD. Positive control: Mouse LRP5-pSEC-tag-transfected 293T cells, MCF-7 human breast adenocarcinoma, T47D human breast ductal carcinoma, and NIH-3T3 mouse embryo fibroblast lysates.


PBS, pH 7.4, 0.1% sodium azide, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About LRP5

O75197 NM_002335 NP_002326.2

LRP5 Antibody, EVR1 Antibody, Exudative vitreoretinopathy 1 Antibody, LRP7 Antibody, OPTA1 Antibody, OPPG Antibody, OPS Antibody, LR3 Antibody, LRP-5 Antibody, VBCH2 Antibody, BMND1 Antibody, EVR4 Antibody

Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.

Requested From: 
Date Requested: 4/23/2017

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