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Anti-LRP2 / Megalin Antibody (aa4641-4655) IHC-plus™ LS-B105

Note: This antibody replaces LS-C3335

Catalog	Size	Price
LS-B105-50	50 µg (1 mg/ml)	Unavailable

Related Products

24 LRP2 / Megalin Antibodies

Most Popular LRP2 / Megalin Antibodies

Anti-LRP2 / Megalin Antibody (aa4641-4655) IHC-plus™ LS-B105

Antibody:	Rabbit Polyclonal to Human LRP2 / Megalin
Reactivity:	Human
Application:	IHC - Paraffin, ELISA
Format:	Unconjugated

Anti-Megalin antibody IHC of human kidney cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B105 concentration 5 ug/ml.

Anti-LRP2 / Megalin Antibody (N-Terminus) LS-C47074

Antibody:	Rabbit Polyclonal to Human LRP2 / Megalin
Reactivity:	Human
Application:	Western blot, ELISA
Format:	Unconjugated

Anti-LRP2 / Megalin Antibody (C-Terminus) LS-C145128

Antibody:	Rabbit Polyclonal to Human LRP2 / Megalin
Reactivity:	Human
Application:	IHC, Western blot, ELISA
Format:	Unconjugated

Anti-LRP2 / Megalin Antibody (aa4035-4184) IHC-plus™ LS-B15008

Antibody:	Rabbit Polyclonal (IgG) to Human LRP2 / Megalin
Reactivity:	Human
Application:	IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Format:	Unconjugated

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-LRP2 / Megalin Antibody IHC-plus™ LS-B15411

Antibody:	Rabbit Polyclonal (IgG) to Human LRP2 / Megalin
Reactivity:	Human, Mouse, Rat
Application:	IHC, IHC - Paraffin, Western blot
Format:	Unconjugated

Immunohistochemistry of paraffin-embedded rat kidney tissue.

(1)

Antibody:	Rabbit Polyclonal to Human LRP2 / Megalin
Reactivity:	Human
Application:	IHC - Paraffin, ELISA
Format:	Unconjugated

Details

Target:	Human LRP2 / Megalin
Host:	Rabbit
Reactivity:	Human (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Protein G purified
Modifications:	Unmodified

Applications

Approved:

IHC - Paraffin (2.5 µg/ml)
ELISA (1:1000)

Specificity and Use

Immunogen:	LRP2 / Megalin antibody was raised against synthetic peptide from human LRP2 / Megalin.
Epitope:	aa4641-4655
Usage:	Immunohistochemistry: LS-B105 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B105 was determined to be 2.5 ug/ml.

Packaging

Presentation:	PBS, 0.09% sodium azide.
Storage:	Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions:	For research use only.

Publications (1)

Apelin retards the progression of diabetic nephropathy. Day RT, Cavaglieri RC, Feliers D. American journal of physiology. Renal physiology. 2013 Mar;304:F788-800. [Full Text Article] [PubMed:23303408] [PMC:PMC3602700]

About LRP2 / Megalin

Uniprot: P98164 NCBI: NM_004525 NP_004516.2

Synonyms: LRP2 Antibody, DBS Antibody, Glycoprotein 330 Antibody, gp330 Antibody, Megalin Antibody, LRP-2 Antibody, Calcium sensor protein Antibody

Description: LRP2 / Megalin, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail.

(More About LRP2 / Megalin)

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Immunohistochemistry

Anti-Megalin antibody IHC of human kidney cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B105 concentration 5 ug/ml.

Requested From:
Date Requested: 4/20/2018

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