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LRP2 / Megalin Antibody (aa4641‑4655) IHC‑plus™ LS‑B105
Note: This antibody replaces LS-C3335
Megalin antibody LS-B105 is an unconjugated rabbit polyclonal antibody to human Megalin (LRP2). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
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Review This ProductPopular LRP2 / Megalin Products
Species:
Human
Applications:
IHC, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Product Description
Megalin antibody LS-B105 is an unconjugated rabbit polyclonal antibody to human Megalin (LRP2). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
About LRP2 / Megalin
LRP2 / Megalin, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail.
P98164
NM_004525
NP_004516.2
LRP2 Antibody, DBS Antibody, Glycoprotein 330 Antibody, gp330 Antibody, Megalin Antibody, LRP-2 Antibody, Calcium sensor protein Antibody
Specifications
Target
Human LRP2 / Megalin
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
- IHC
- IHC - Paraffin (2.5 µg/ml)
- ELISA (1:1000)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Immunogen
LRP2 / Megalin antibody was raised against synthetic peptide from human LRP2 / Megalin.
Epitope
aa4641-4655
Usage
Immunohistochemistry: LS-B105 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B105 was determined to be 2.5 ug/ml.
Presentation
PBS, 0.09% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
Publications (1)
1
Apelin retards the progression of diabetic nephropathy. Day RT, Cavaglieri RC, Feliers D. American journal of physiology. Renal physiology. 2013 Mar;304:F788-800. [Full Text Article]
[PubMed:23303408]
[PMC:PMC3602700]
Customer Reviews (0)
Images
Immunohistochemistry
Anti-Megalin antibody IHC of human kidney cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B105 concentration 5 ug/ml.
Immunohistochemistry
Anti-Megalin antibody IHC of human kidney cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B105 concentration 5 ug/ml.
Immunohistochemistry
Anti-Megalin antibody IHC of human kidney cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B105 concentration 5 ug/ml.
Immunohistochemistry
Anti-Megalin antibody IHC of human kidney cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B105 concentration 5 ug/ml.
Requested From: United States
Date Requested: 7/22/2018
Date Requested: 7/22/2018
