Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1.
Gene Name: | tripartite motif containing 71, E3 ubiquitin protein ligase |
Synonyms: | TRIM71, Abnormal cell LINeage LIN-41, Homolog of C. elegans Lin-41, Protein lin-41 homolog, LIN41, Tripartite motif containing 71, Tripartite motif-containing 71, LIN-41 |
Target Sequences: | NP_001034200.1 Q2Q1W2 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.