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Anti-LDLR / LDL Receptor Antibody (Internal, DY550) LS-C142550

Ordering

Wt. Vol. Conc. Price
- 100 µl - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular LDLR / LDL Receptor Antibodies

Anti-LDLR / LDL Receptor Antibody (aa499-511) IHC-plus™ LS-B1598
Rabbit Polyclonal (IgG) to Mouse LDLR / LDL Receptor
Mouse, Human
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-LDLR / LDL Receptor Antibody (Extracellular Domain, PE) LS-C130473
Mouse Monoclonal (IgG1) to Human LDLR / LDL Receptor
Human
Flow Cytometry
PE Conjugated
Anti-LDLR / LDL Receptor Antibody LS-C146979
Rabbit Polyclonal to Human LDLR / LDL Receptor
Human, Mouse, Rat, Bovine, Hamster
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human LDLR / LDL Receptor
Human, Monkey
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
DY550 Conjugated

Details

Human LDLR / LDL Receptor
Rabbit
Human, Monkey (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
Polyclonal
DyLight 550. Also available Unconjugated or conjugated with Biotin, DY650, DY488.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot (0.5 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

LDLR / LDL Receptor antibody was raised against synthetic peptide made to an internal portion of the human protein (within residues 500-550). [Swiss-Prot# P01130]. Percent identity by BLAST analysis: Monkey (100%); Mouse (92%).
Internal
Both the unglycosylated and glycosylated forms of the LDL Receptor.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

50 mM sodium borate
Store at 4°C. Do not freeze.
For research use only.

About LDLR / LDL Receptor

P01130 NM_000527 NP_000518.1

LDLR Antibody, FHC Antibody, LDL receptor Antibody, LDLCQ2 Antibody

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis.

Immunohistochemistry

Immunohistochemistry
Anti-LDLR / LDL Receptor antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10039 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
LDL Receptor Antibody - Western Blot on HepG2 whole cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/7/2016

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