Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Human (tested or 100% immunogen sequence identity)
Protein A purified
IHC - Frozen
Specificity and Use
L1CAM antibody was raised against homogenate of 16 week human fetal brain cells.
Recognizes the 220-240kD glycoprotein L1 molecule which is expressed in neural tissues, neuroblastoma and medulloblastoma. NCAM L1 expression also occurs on cells of myelomonocytic and lymphoid origin.
Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry and Immunoprecipitation. Immunohistochemistry: Frozen sections.
PBS, pH 7.2, 1 mg/ml BSA, 10 mM sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation.