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Anti-KLRD1 / CD94 Antibody (Biotin) LS-C44494

Note: This antibody replaces LS-C57778
Catalog Size Price
LS-C44494-100 100 µg (0.1 mg/ml) Unavailable

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Formalin-fixed and paraffin-embedded human lymph with KLRD1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

100% Guaranteed
Mouse Monoclonal (IgG1) to Human KLRD1 / CD94
Flow Cytometry
Biotin Conjugated


Human KLRD1 / CD94
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein G purified


Flow Cytometry (1:1)

Specificity and Use

KLRD1 / CD94 antibody was raised against natural killer cell line.
Specific for human CD94, also known as KLRD1 (Killer cell lectin-like receptor, subfamily D, member 1). CD94 is expressed on natural killer (NK) cells and a subset of T lymphocytes. CD94 is found to associate with NKG2 to form a heterodimer which is involved in the inhibition of cell mediated cytotoxicity against cells bearing appropriate MHC class I allotypes. Clone DX22 is reported to inhibit the binding of CD94 to HLA-E(2) and HLA-G(4). XXX recommend the use of MCA2254XZ for functional studies.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1 x 10^6 cells in 100 ul. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.


PBS, pH 7.4, 0.09% sodium azide, 1.0% BSA.
For research use only.

About KLRD1 / CD94

Q13241 NM_002262 NP_002253.1

KLRD1 Antibody, CD94 Antibody, KP43 Antibody, NK cell receptor Antibody, CD94 antigen Antibody

Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus.

Requested From: 
Date Requested: 5/25/2018

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