LSBio The Immunohistochemistry Antibody Company
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-KLRB1 / CD161 Antibody (clone 10/78) LS-C43596

Note: This antibody replaces LS-C43591

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $225
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular KLRB1 / CD161 Antibodies

Anti-KLRB1 / CD161 Antibody (clone B199.2, Biotin) LS-C35855
Mouse Monoclonal [clone B199.2] (IgG2b) to Human KLRB1 / CD161
Human
Flow Cytometry
Biotin Conjugated
Anti-KLRB1 / CD161 Antibody (clone B199.2) LS-C123172
Mouse Monoclonal [clone B199.2] (IgG2b) to Human KLRB1 / CD161
Human
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-KLRB1 / CD161 Antibody (aa68-225, clone 14F1F11) LS-C359302
Mouse Monoclonal [clone 14F1F11] (IgG1,k) to Human KLRB1 / CD161
Human
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 10/78] (IgG1) to Rat KLRB1 / CD161
Rat
IHC - Frozen, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Unconjugated

Details

Rat KLRB1 / CD161
Mouse
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [10/78]
Unconjugated. Also available conjugated with Biotin, FITC, FITC, FITC, RPE.
Protein G purified
Unmodified. Also available Azide-free.

Applications

  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:50 - 1:100)
  • (applications tested for the base form of this product only)

Specificity and Use

KLRB1 / CD161 antibody was raised against purified splenic NK cells from the LEW rat strain.
Recognizes the rat Killer cell lectin-like receptor subfamily B protein, also known as NKR-PI or CD161. CD161 is a 233 amino acid ~60 kD type II single pass protein containing a single domain. CD161 is expressed on rat NK cells and T cell subpopulations. CD161 exists in 2 forms NKR-PIa and NKR-PIb, clone 10/78 Ârecognizes both forms of CD161. Clone 10/78 competes with another anti CD161 clone, 3.2.3 for binding to antigen. Has been successfully employed for the in vivo depletion of rat NK cells in an experimental obesity model.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
For research use only.

About KLRB1 / CD161

Q12918 NM_002258 NP_002249.1

KLRB1 Antibody, CD161 antigen Antibody, CLEC5B Antibody, CD161 Antibody, NKR-P1A Antibody, NKR Antibody, HNKR-P1A Antibody, NKR-P1 Antibody, NKRP1A Antibody

Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope.

Requested From: United States
Date Requested: 12/2/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number