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Anti-KLRB1 / CD161 Antibody (clone 10/78) LS-C43596

Note: This antibody replaces LS-C43591
Catalog Size Price
LS-C43596-100 100 µg (1 mg/ml) Unavailable

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63 KLRB1 / CD161 Antibodies

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Anti-KLRB1 / CD161 Antibody (clone B199.2, Biotin) LS-C35855
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Anti-KLRB1 / CD161 Antibody LS-C123171
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Anti-KLRB1 / CD161 Antibody (clone B199.2) LS-C123172
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Anti-KLRB1 / CD161 Antibody (aa68-225, clone 14F1F11) LS-C359302
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Western Blot: CD161 Antibody (14F1F11) - Western blot analysis of a partial CD161 recombinant protein using CD161 antibody at 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-KLRB1 / CD161 Antibody LS-C409088
Rabbit Polyclonal (IgG) to Human KLRB1 / CD161
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Western blot blot of extracts of various cell lines, using KLRB1 antibody.

100% Guaranteed
Mouse Monoclonal [clone 10/78] (IgG1) to Rat KLRB1 / CD161
IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)


Rat KLRB1 / CD161
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [10/78]
Unconjugated. Also available conjugated with Biotin, FITC, FITC, FITC, RPE.
Protein G purified
Unmodified. Also available Azide-free.


  • IHC
  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:50 - 1:100)
  • (applications tested for the base form of this product only)

Specificity and Use

KLRB1 / CD161 antibody was raised against purified splenic NK cells from the LEW rat strain.
Recognizes the rat Killer cell lectin-like receptor subfamily B protein, also known as NKR-PI or CD161. CD161 is a 233 amino acid ~60 kD type II single pass protein containing a single domain. CD161 is expressed on rat NK cells and T cell subpopulations. CD161 exists in 2 forms NKR-PIa and NKR-PIb, clone 10/78 Ârecognizes both forms of CD161. Clone 10/78 competes with another anti CD161 clone, 3.2.3 for binding to antigen. Has been successfully employed for the in vivo depletion of rat NK cells in an experimental obesity model.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.


PBS, pH 7.4, 0.09% sodium azide.
For research use only.

About KLRB1 / CD161

Q12918 NM_002258 NP_002249.1

KLRB1 Antibody, CD161 antigen Antibody, CLEC5B Antibody, CD161 Antibody, NKR-P1A Antibody, NKR Antibody, HNKR-P1A Antibody, NKR-P1 Antibody, NKRP1A Antibody

Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope.

Requested From: 
Date Requested: 5/22/2018

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