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Anti-KLRB1 / CD161 Antibody (Azide-free) LS-C14352

Catalog Size Price
LS-C14352-1000 1000 µg Unavailable

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100% Guaranteed
Mouse Monoclonal (IgG1) to Rat KLRB1 / CD161
Western blot, Immunoprecipitation, Flow Cytometry, Functional Assay, Radioimmunoassay
Unconjugated, Azide-free


Rat KLRB1 / CD161
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein G purified


  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:50 - 1:100)
  • Functional Assay
  • Radioimmunoassay

Specificity and Use

KLRB1 / CD161 antibody was raised against purified splenic NK cells from the LEW rat strain.
Recognizes the rat CD161 protein (also known as NKR-PI) a 60kD glycoprotein expressed on rat NK cells and T cell subpopulations. This antibody competes with clone 3.2.3 for binding to the antigen. Clone 3H1914 stimulates NK mediated cytotoxicity in a manner identical to clone 3.2.3.
Immunoprecipitation. Western Blot. Radioimmunoassay. Functional Studies. Flow Cytometry: 1:50-1:100. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.


Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About KLRB1 / CD161

Q12918 NM_002258 NP_002249.1

KLRB1 Antibody, CD161 antigen Antibody, CLEC5B Antibody, CD161 Antibody, NKR-P1A Antibody, NKR Antibody, HNKR-P1A Antibody, NKR-P1 Antibody, NKRP1A Antibody

Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope.

Requested From: 
Date Requested: 2/17/2018

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