Human KIAA1811 / BRSK1
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
- IHC - Paraffin (5 µg/ml)
- Western blot (0.5 - 1 µg/ml)
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A peptide corresponding to a 28 amino acid sequence from near the centre of Human BRSK1.
Recognizes human BR serine-threonine kinase 1 (BRSK1), a cytoplasmic and nuclear protein belonging to the protein kinase super family. BRSK1 is a widely expressed protein, with highest levels being detected in the brain and testis. It is essential for the polarization forebrain neurons which results in the distinct properties of axons and dendrites. BRSK1 is involved in the regulation of G2/M arrest and functions as a checkpoint kinase following UV- or methyl methane sulfonate (but not IR-) induced DNA damage. BRSK1 phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. Multiple isoforms of BRSK1 have been identified.
PBS, 0.02% sodium azide
4°C or -20°C, Avoid freeze-thaw cycles.
For research use only.
This antibody carries the LSBio 100% Guarantee.