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Anti-KIAA1811 / BRSK1 Antibody LS-C187781

Catalog Size Price
LS-C187781-100 100 µg (1 mg/ml) Unavailable

Most Popular KIAA1811 / BRSK1 Antibodies

Anti-KIAA1811 / BRSK1 Antibody (C-Terminus) IHC-plus™ LS-B180
Rabbit Polyclonal (IgG) to Human KIAA1811 / BRSK1
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-KIAA1811 / BRSK1 Antibody (Internal) IHC-plus™ LS-B181
Rabbit Polyclonal (IgG) to Human KIAA1811 / BRSK1
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-KIAA1811 / BRSK1 Antibody LS-C127086
Rabbit Monoclonal (IgG) to Human KIAA1811 / BRSK1
Human, Mouse, Rat
Western blot, Immunoprecipitation
Unconjugated
Anti-KIAA1811 / BRSK1 Antibody (C-Terminus) LS-C319888
Rabbit Polyclonal (IgG) to Human KIAA1811 / BRSK1
Human
IHC, Western blot, ELISA
Unconjugated
Anti-KIAA1811 / BRSK1 Antibody LS-C501399
Rabbit Polyclonal (IgG) to Human KIAA1811 / BRSK1
Human, Mouse
IHC, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed
Rabbit Polyclonal (IgG) to Human KIAA1811 / BRSK1
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated

Details

Human KIAA1811 / BRSK1
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.5 - 1 µg/ml)

Specificity and Use

A peptide corresponding to a 28 amino acid sequence from near the centre of Human BRSK1.
Recognizes human BR serine-threonine kinase 1 (BRSK1), a cytoplasmic and nuclear protein belonging to the protein kinase super family. BRSK1 is a widely expressed protein, with highest levels being detected in the brain and testis. It is essential for the polarization forebrain neurons which results in the distinct properties of axons and dendrites. BRSK1 is involved in the regulation of G2/M arrest and functions as a checkpoint kinase following UV- or methyl methane sulfonate (but not IR-) induced DNA damage. BRSK1 phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. Multiple isoforms of BRSK1 have been identified.

Packaging

PBS, 0.02% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About KIAA1811 / BRSK1

Q8TDC3 AB058714 BAB47440.1

BRSK1 Antibody, BR serine/threonine kinase 1 Antibody, Brain-selective kinase 1 Antibody, KIAA1811 Antibody, HSAD1 Antibody, Protein kinase SAD1A Antibody, SAD1 Antibody, SadB kinase short isoform Antibody, SAD1 homolog Antibody, SAD1 kinase Antibody, SADB Antibody

Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Thr-529' and 'Ser-579'.

Requested From: 
Date Requested: 10/17/2017

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