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Anti-KDM5B / JARID1B Antibody (DY488) LS-C181915

Ordering

Wt. Vol. Conc. Price
- 100 µl 0.828 mg/ml $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular KDM5B / JARID1B Antibodies

Anti-KDM5B / JARID1B Antibody (clone 1G10) LS-C133659
Mouse Monoclonal [clone 1G10] (IgG2a,k) to Human KDM5B / JARID1B
Human
Immunofluorescence, Western blot, ELISA
Unconjugated
Immunofluorescence Image
Anti-KDM5B / JARID1B Antibody (aa192-224) LS-C165353
Rabbit Polyclonal to Human KDM5B / JARID1B
Human, Mouse
Western blot
Unconjugated
Western blot Image
Anti-KDM5B / JARID1B Antibody (aa1494-1544) LS-C288593
Rabbit Polyclonal (IgG) to Human KDM5B / JARID1B
Human, Mouse, Dog
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human KDM5B / JARID1B
Human
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry (applications tested for the base form of this product only)
DY488 Conjugated

Details

Human KDM5B / JARID1B
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
DyLight 488. Also available Unconjugated or conjugated with Biotin, DY650, DY550.
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (1:200)
  • ICC (1:100)
  • Immunofluorescence
  • Western blot
  • Flow Cytometry
  • (applications tested for the base form of this product only)

  • Western blot

Specificity and Use

KDM5B / JARID1B antibody was raised against a synthetic peptide made to an internal portion of the human JARID1B protein (between residues 800-850) [UniProt Q9UGL1].
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

50 mM sodium borate
Store at 4°C in the dark.
For research use only.

About KDM5B / JARID1B

Q9UGL1 NM_006618 NP_006609.3

KDM5B Antibody, CT31 Antibody, JARID1B Antibody, Histone demethylase JARID1B Antibody, RBBP2H1A Antibody, Lysine-specific demethylase 5B Antibody, PUT1 Antibody, RBP2-H1 Antibody, Cancer/testis antigen 31 Antibody, PLU-1 Antibody, PLU1 Antibody, RBBP2H1 Antibody

Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry: JARID1B Antibody - IHC analysis of JARID1B in human breast cancer xenograft using DAB with hematoxylin counterstain. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunofluorescence

Immunofluorescence
Immunocytochemistry/Immunofluorescence: JARID1B Antibody - Jarid1B / KDM5B antibody was tested in HeLa cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/3/2016

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