Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. Insensitive to tetraethylammonium, but inhibited by barium, linopirdine and XE991. Activated by niflumic acid and the anticonvulsant retigabine. Muscarine suppresses KCNQ5 current in Xenopus oocytes in which cloned KCNQ5 channels were coexpressed with M1 muscarinic receptors.
Gene Name: | potassium voltage-gated channel, KQT-like subfamily, member 5 |
Family/Subfamily: | Ion Channel , Potassium channel - KCNQ |
Synonyms: | KCNQ5, KQT-like 5, Kv7.5, Potassium channel protein |
Target Sequences: | NM_019842 NP_062816.2 Q9NR82 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.