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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KCNMA1 / BK Antibody (Internal) IHC‑plus™ LS‑A9574
BK antibody LS-A9574 is an unconjugated rabbit polyclonal antibody to BK (KCNMA1) from human, mouse, rat and other species. Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-A9574-50
50 µg (0.8 mg/ml)
Unavailable
In Stock for Immediate Shipment

Popular KCNMA1 / BK Products

Antibody
Species: Mouse, Rat
Applications: IHC, Western blot
Anti-KCNMA1 antibody LS-A9575 IHC of human breast, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Applications: IHC, IHC - Paraffin
Anti-KCNMA1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6604 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Product Description

BK antibody LS-A9574 is an unconjugated rabbit polyclonal antibody to BK (KCNMA1) from human, mouse, rat and other species. Validated for IHC. Tested on 20 paraffin-embedded human tissues.
About KCNMA1 / BK
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca2+ that mediates export of K+. It is also activated by the concentration of cytosolic Mg2+. Its activation dampens the excitatory events that elevate the cytosolic Ca2+ concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Q12791 NM_002247 NP_002238.2

KCNMA1 Antibody, BA205K10.1 Antibody, BKCA alpha subunit Antibody, BK channel Antibody, BKCA alpha Antibody, BKTM Antibody, HSlo Antibody, K(VCA)alpha Antibody, KCa1.1 Antibody, Maxi-K channel HSLO Antibody, MaxiK Antibody, KCNMA Antibody, SAKCA Antibody, SLO-ALPHA Antibody, Slowpoke homolog Antibody, Stretch-activated Kca channel Antibody, Slo homolog Antibody, BK channel alpha subunit Antibody, Maxi K channel Antibody, MSlo Antibody, MSLO1 Antibody, SLO Antibody, SLO1 Antibody


Specifications

Target
Human KCNMA1 / BK
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Pig, Rabbit, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2.5 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
KCNMA1 / BK antibody was raised against synthetic 15 amino acid peptide from internal region of human KCNMA1. Percent identity with other species by BLAST analysis: Human, Monkey, Mouse, Rat, Hamster, Bovine, Dog, Rabbit, Pig, Turkey, Chicken, Xenopus, Seabass, Stickleback, Pufferfish, Zebrafish (100%).
Blocking Peptide
LS-E29691 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A9574. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Internal
Specificity
Human KCNMA1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, less than 0.1% sodium azide.
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-KCNMA1 antibody LS-A9574 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-KCNMA1 antibody LS-A9574 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-KCNMA1 antibody LS-A9574 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-KCNMA1 antibody LS-A9574 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-KCNMA1 antibody LS-A9574 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-KCNMA1 antibody LS-A9574 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-KCNMA1 antibody LS-A9574 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-KCNMA1 antibody LS-A9574 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.


Requested From: 
Date Requested: 6/21/2018

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