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Anti-KCNC3 / Kv3.3 Antibody (aa651-663) LS-C154944

Catalog	Size	Price
LS-C154944-100	100 µg (0.5 mg/ml)	Unavailable

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21 KCNC3 / Kv3.3 Antibodies

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Anti-KCNC3 / Kv3.3 Antibody (aa468-517) LS-C101533

Antibody:	Rabbit Polyclonal (IgG) to Human KCNC3 / Kv3.3
Reactivity:	Human, Monkey, Mouse, Rat, Guinea pig, Pig, Rabbit
Application:	Western blot
Format:	Unconjugated

Anti-KCNC3 / Kv3.3 Antibody (N-Terminus) LS-C144788

Antibody:	Rabbit Polyclonal to Human KCNC3 / Kv3.3
Reactivity:	Human
Application:	IHC, Western blot
Format:	Unconjugated

Anti-KCNC3 / Kv3.3 Antibody (aa651-663) LS-C154944

Antibody:	Goat Polyclonal to Mouse KCNC3 / Kv3.3
Reactivity:	Mouse, Rat
Application:	Western blot, ELISA
Format:	Unconjugated

Anti-KCNC3 / Kv3.3 Antibody (clone 1C1) LS-C197570

Antibody:	Mouse Monoclonal [clone 1C1] (IgG1,k) to Human KCNC3 / Kv3.3
Reactivity:	Human, Mouse
Application:	Immunofluorescence, Western blot, ELISA
Format:	Unconjugated

Anti-KCNC3 / Kv3.3 Antibody (aa638-667) LS-C322375

Antibody:	Rabbit Polyclonal (IgG) to Human KCNC3 / Kv3.3
Reactivity:	Human
Application:	Western blot, ELISA
Format:	Unconjugated

Antibody:	Goat Polyclonal to Mouse KCNC3 / Kv3.3
Reactivity:	Mouse, Rat
Application:	Western blot, ELISA
Format:	Unconjugated

Details

Target:	Mouse KCNC3 / Kv3.3
Host:	Goat
Reactivity:	Mouse, Rat (tested or 100% immunogen sequence identity)
Predicted:	Human, Monkey, Rabbit (at least 90% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

Western blot (0.2 - 0.6 µg/ml)
ELISA (1:64000)

Specificity and Use

Immunogen:

KCNC3 / Kv3.3 antibody was raised against synthetic peptide C-QEEVIETNRADPR from an internal region of mouse KCNC3 / Kv3.3 (NP_032448.2). Percent identity by BLAST analysis: Mouse, Rat (100%); Human, Orangutan, Gibbon, Monkey, Galago, Marmoset, Panda, Rabbit, Porcine (92%); Guinea pig (85%).

Blocking Peptide:

LS-E27809 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C154944. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

aa651-663

Specificity:

Mouse KCNC3 / Kv3.3.

Usage:

Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 80kD band observed in Mouse fetal Brain lysates (calculated MW of 81.9kD according to NP_032448.2). Recommended concentration: 0.2-0.6 ug/ml. Some minor background is detected and is blocked by the immunizing peptide. We call for caution when used for other assays than Western blot.

Packaging

Presentation:	Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage:	Store at -20°C. Avoid freeze-thaw cycles.
Restrictions:	For research use only.

About KCNC3 / Kv3.3

Uniprot: Q14003 NCBI: NM_004977 NP_004968.2

Synonyms: KCNC3 Antibody, KSHIIID Antibody, SCA13 Antibody, Spinocerebellar ataxia 13 Antibody, KV3.3 Antibody

Description: This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

(More About KCNC3 / Kv3.3)

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Western blot

KCNC3 antibody (0.2 ug/ml) staining of Mouse fetal Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From:
Date Requested: 8/16/2017

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