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Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR).
Gene Name: | intersectin 2 |
Synonyms: | ITSN2, Intersectin-2, KIAA1256, PRO2015, SH3 domain protein 1B, SH3P18, SWA, Intersectin 2, SH3D1B, SWAP |
Target Sequences: | NM_019595 Q9NZM3 Q9NZM3 |
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