Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Rat ITGB3 / Integrin Beta 3 / CD61
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Rat ITGB3 / Integrin Beta 3 / CD61
Rat, Human (tested or 100% immunogen sequence identity)
IHC - Frozen
Specificity and Use
ITGB3 / Integrin Beta 3 / CD61 antibody was raised against cell preparation: A bone cell suspension containing osteoclasts, osteoblasts and bone marrow cells obtained from the long bones of newborn Sprague Dawley rats.
MHF4 may be used to identify osteoclasts in tissue sections and bone cell suspensions. Species cross-reactivity: Cross-reacts with Human and Rat. Not yet tested in other species.
Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry (Fr).
Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands.