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Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody LS-C152905

Catalog Size Price
LS-C152905-100 100 µg (1 mg/ml) Unavailable

Most Popular ITGB3 / Integrin Beta 3 / CD61 Antibodies

Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody (N-Terminus) IHC-plus™ LS-A9416
Rabbit Polyclonal to Human ITGB3 / Integrin Beta 3 / CD61
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody LS-C13870
Mouse Monoclonal (IgG1) to Human ITGB3 / Integrin Beta 3 / CD61
Human
Western blot, Flow Cytometry, Functional Assay
Unconjugated
Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody (clone VI-PL2) IHC-plus™ LS-B4046
Mouse Monoclonal [clone VI-PL2] (IgG1,k) to Human ITGB3 / Integrin Beta 3 / CD61
Human
IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody (FITC) LS-C130089
Mouse Monoclonal (IgG1) to Pig ITGB3 / Integrin Beta 3 / CD61
Pig, Human, Bovine, Dog, Horse
Flow Cytometry
FITC Conjugated
Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody (clone 2f2) LS-C311998
Mouse Monoclonal [clone 2f2] (IgG1,k) to Human ITGB3 / Integrin Beta 3 / CD61
Human
IHC - Paraffin, IHC - Frozen
Unconjugated
Immunohistochemistry Image

100% Guaranteed
Mouse Monoclonal (IgM) to Human ITGB3 / Integrin Beta 3 / CD61
Human
ICC, Immunoprecipitation, Flow Cytometry, Functional Assay
Unconjugated

Details

Human ITGB3 / Integrin Beta 3 / CD61
Mouse
Human (tested or 100% immunogen sequence identity)
IgM Monoclonal
Unconjugated
Purified
Unmodified

Applications

  • ICC
  • Immunoprecipitation
  • Flow Cytometry
  • Functional Assay

Specificity and Use

Normal blood mononuclear cells activated by mixed lymphocyte reaction and cultured for 10 days in medium containing IL-2
Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61. The apparent molecular weight of the GPIIIa by SDS-PAGE is 105 kD reduced and 90 kD unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. The monocytoid cell line U937 is highly positive. (original paper claimed IgG2ak)
Immunoprecipitation. Immunocytochemistry (acetone fixation required). Flow cytometry. Inhibits platelet aggregation, 10 ug/ml. Optimal working dilutions must be determined by end user.

Packaging

0.02 M phosphate buffer, pH 7.6, 0.25 M sodium chloride, 0.1% sodium azide
Store at 4°C.
For research use only.

About ITGB3 / Integrin Beta 3 / CD61

P05106 NM_000212 NP_000203.2

ITGB3 Antibody, BDPLT2 Antibody, CD61 antigen Antibody, GT Antibody, gp3A Antibody, CD61 Antibody, GPIIIa Antibody, Integrin beta-3 Antibody

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands.

Requested From: 
Date Requested: 10/21/2017

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