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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ITGB1 / Integrin Beta 1 / CD29 Antibody (clone TS2/16) LS‑C40964
CD29 antibody LS-C40964 is an unconjugated mouse monoclonal antibody to human CD29 (ITGB1 / Integrin Beta 1). Validated for Flow, IHC and IP. Cited in 3 publications.
Catalog
Size
Price
LS-C40964-100
100 µg (0.5 mg/ml)
Unavailable

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Product Description

CD29 antibody LS-C40964 is an unconjugated mouse monoclonal antibody to human CD29 (ITGB1 / Integrin Beta 1). Validated for Flow, IHC and IP. Cited in 3 publications.
About ITGB1 / Integrin Beta 1 / CD29
Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. P05556 NM_002211 NP_002202.2

ITGB1 Antibody, CD29 Antibody, CD29 antigen Antibody, Integrin beta-1 Antibody, MDF2 Antibody, MSK12 Antibody, Integrin VLA-4 beta subunit Antibody, VLA-BETA Antibody, VLAB Antibody, Beta 1 integrin Antibody, FNRB Antibody, GPIIA Antibody, Integrin Beta 1 Antibody, VLA-4 subunit beta Antibody


Specifications

Target
Human ITGB1 / Integrin Beta 1 / CD29
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [TS2/16]
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Used in IHC with acetone-fixed frozen tissue sections.
Presentation
PBS, pH 7.2, 0.09% sodium azide.
Storage
4°C, avoid freezing.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (3)

1
Prostate-specific membrane antigen regulates angiogenesis by modulating integrin signal transduction. Conway RE, Petrovic N, Li Z, Heston W, Wu D, Shapiro LH. Molecular and cellular biology. 2006 26:5310-24. [PubMed:16809768] [PMC:PMC1592718]
2
Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers. Pillozzi S, Masselli M, De Lorenzo E, Accordi B, Cilia E, Crociani O, Amedei A, Veltroni M, D'Amico M, Basso G, Becchetti A, Campana D, Arcangeli A. Blood. 2011 117:902-14. [PubMed:21048156]
3
KCNQ5/K(v)7.5 potassium channel expression and subcellular localization in primate retinal pigment epithelium and neural retina. Zhang X, Yang D, Hughes BA. American journal of physiology. Cell physiology. 2011 301:C1017-26. [PubMed:21795522] [PMC:PMC3213923]

Customer Reviews (0)


Images


Immunohistochemistry

BT474 breast cancer cells were stained with anti-CD29 (clone TS2/16) followed by DyLight 649 Goat anti-mouse Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.
BT474 breast cancer cells were stained with anti-CD29 (clone TS2/16) followed by DyLight 649 Goat anti-mouse Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.

Flow Cytometry

Human peripheral blood lymphocytes stained with purified TS2/16, followed by anti-mouse IgGs FITC
Human peripheral blood lymphocytes stained with purified TS2/16, followed by anti-mouse IgGs FITC

Immunohistochemistry

BT474 breast cancer cells were stained with anti-CD29 (clone TS2/16) followed by DyLight 649 Goat anti-mouse Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.
BT474 breast cancer cells were stained with anti-CD29 (clone TS2/16) followed by DyLight 649 Goat anti-mouse Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.

Flow Cytometry

Human peripheral blood lymphocytes stained with purified TS2/16, followed by anti-mouse IgGs FITC
Human peripheral blood lymphocytes stained with purified TS2/16, followed by anti-mouse IgGs FITC

Immunohistochemistry

BT474 breast cancer cells were stained with anti-CD29 (clone TS2/16) followed by DyLight 649 Goat anti-mouse Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.
BT474 breast cancer cells were stained with anti-CD29 (clone TS2/16) followed by DyLight 649 Goat anti-mouse Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.

Flow Cytometry

Human peripheral blood lymphocytes stained with purified TS2/16, followed by anti-mouse IgGs FITC
Human peripheral blood lymphocytes stained with purified TS2/16, followed by anti-mouse IgGs FITC

Immunohistochemistry

BT474 breast cancer cells were stained with anti-CD29 (clone TS2/16) followed by DyLight 649 Goat anti-mouse Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.
BT474 breast cancer cells were stained with anti-CD29 (clone TS2/16) followed by DyLight 649 Goat anti-mouse Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.

Flow Cytometry

Human peripheral blood lymphocytes stained with purified TS2/16, followed by anti-mouse IgGs FITC
Human peripheral blood lymphocytes stained with purified TS2/16, followed by anti-mouse IgGs FITC


Requested From: 
Date Requested: 6/20/2018

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