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Anti-ITGAM / CD11b Antibody (Internal, clone EPR1344) IHC-plus™ LS-B6253

Note: This antibody replaces LS-C105666
See our new ITGAM / CD11b ELISA Kits
Rat ITGAM / CD11b ELISA Kit - LS-F4904
Human ITGAM / CD11b ELISA Kit - LS-F9298
Human ITGAM / CD11b ELISA Kit - LS-F11850
(kits do not necessarily contain the antibody listed on this page)

Ordering

Wt. Vol. Conc. Price
- 50 µl - $395

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

ITGAM / CD11b Antibody LS-B6253 Images

[click image for a larger image and more details]
Immunohistochemistry
Anti-CD11b antibody IHC of human spleen.
Western blot
Western blot analysis on (A) THP-1 +TPA (B) TF-1 cell lysates using anti-CD11b antibody (LS-B6253).

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Rabbit Monoclonal [clone EPR1344] (IgG) to Human ITGAM / CD11b
Human
IHC - Paraffin, ICC, Western blot, Flow Cytometry
Unconjugated

Details

Human ITGAM / CD11b
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Monoclonal [EPR1344]
Tissue culture supernatant

Applications

IHC - Paraffin (1:50), ICC (1:100 - 1:250), Western blot (1:1000 - 1:5000), Flow Cytometry (1:100)

Specificity and Use

ITGAM / CD11b antibody was raised against a synthetic peptide corresponding to residues in human CD11b was used as an immunogen.
Internal

Packaging

Tris-Glycine-NaCl or PBS, pH 7.2-7.4, 40-50% Glycerol, 0.01% sodium azide, 0.05% BSA
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About ITGAM / CD11b

P11215 NM_000632 NP_000623.2

ITGAM Antibody, Antigen CD11b (p170) Antibody, CD11B Antibody, CD11b antigen Antibody, CR3A Antibody, Integrin alpha-M Antibody, MAC-1 Antibody, MO1A Antibody, Neutrophil adherence receptor Antibody, MAC1A Antibody, SLEB6 Antibody, CR-3 alpha chain Antibody

The leukocyte adhesion receptor Mac-1 is a cell surface glycoprotein that plays a fundamental role in the adhesion between myeloid and lymphoid cells. It is composed of alpha/beta heterodimers and expressed on cells of myeloid linage. CD11b constitutes the alpha subunit and is a member the integrin family of proteins. Mac-1 has been shown to be involved in neutrophil aggregation and adhesion to endothelial cells, rosetting of erythrocytes to macrophages and polymorphonuclear leukocytes.

Immunohistochemistry

Immunohistochemistry
Anti-CD11b antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6253 dilution 1:50.

Western blot

Western blot
Western blot analysis on (A) THP-1 +TPA (B) TF-1 cell lysates using anti-CD11b antibody (LS-B6253).
Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Requested From: United States
Date Requested: 4/27/2015

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