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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ITGAM / CD11b Antibody (clone M1/70, Biotin) LS‑C86770
Antibody
CD11b antibody LS-C86770 is a biotin-conjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IHC and IP.
Catalog
Size
Price
LS-C86770-500
500 µg
Unavailable

Popular ITGAM / CD11b Products

Antibody
Species: Rat
Applications: IHC, IHC - Frozen
Antibody
Species: Mouse
Applications: IHC, IHC - Paraffin, IHC - Frozen, Flow Cytometry
Anti-CD11b antibody IHC of mouse spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3760 concentration 10 ug/ml.
Species: Mouse, Human, Rabbit
Applications: IHC, IHC - Paraffin, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Antibody
Species: Bovine, Goat, Sheep
Applications: Flow Cytometry
CD11b Antibody - Microglia Marker - IHC of CD11b in human renal cancer using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Rat
Applications: IHC, IHC - Paraffin

Product Description

CD11b antibody LS-C86770 is a biotin-conjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IHC and IP.
About ITGAM / CD11b
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. P11215 NM_000632 NP_000623.2

ITGAM Antibody, Antigen CD11b (p170) Antibody, CD11B Antibody, CD11b antigen Antibody, CR3A Antibody, Integrin alpha-M Antibody, MAC-1 Antibody, MO1A Antibody, Neutrophil adherence receptor Antibody, MAC1A Antibody, SLEB6 Antibody, CR-3 alpha chain Antibody


Specifications

Target
Mouse ITGAM / CD11b
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal [M1/70]
Conjugations
Biotin
Modifications
Unmodified
Applications
  • IHC
  • Immunoprecipitation
  • Flow Cytometry
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ITGAM / CD11b antibody was raised against c57BL/10 mouse splenic T-Cells and Concanavalin A-activated C57BL/10Splenocytes.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, sodium azide
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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