Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Protein G purified
Western blot (1 - 2 µg/ml)
ELISA (0.5 - 1 µg/ml)
Specificity and Use
ITGA2 / CD49b antibody was raised against cHO-derived rhITGA2. (aa 30 - 1132).
Recognizes human ITGA2 subunit.
Suitable for use in Direct ELISA and Western Blot. Direct ELISA: 0.5-1.0 ug/ml detection limit for rhITGA2 is ~2 ng/well. Western Blot: 1-2 ug/ml detection limit for rhITGA2 is ~5 ng/lane under non-reducing and reducing conditions.
Lyophilized from PBS, 5% trehalose. Reconstitute, 200 ul sterile 40-50% glycerol, PBS.
ITGA2 encodes integrin alpha chain 2. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing alpha integrin 2 combines with beta integrin 1 to form a collagen-binding integrin referred to as glycoprotein Ia/IIa when expressed on platelets, and very late (activation) antigen 2 ('VLA-2') when found on T-cells. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.