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Anti-IRX5 Antibody (aa351-363) IHC-plus™ LS-B3078

Note: This antibody replaces LS-C8290

Ordering

Wt. Vol. Conc. Price
50 µg - 0.2 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular IRX5 Antibodies

Anti-IRX5 Antibody (aa455-483, APC) LS-C260401
Rabbit Polyclonal (IgG) to Human IRX5
Human, Mouse
Western blot, ELISA
APC Conjugated
Anti-IRX5 Antibody (aa455-483, Biotin) LS-C260403
Rabbit Polyclonal (IgG) to Human IRX5
Human, Mouse
Western blot, ELISA
Biotin Conjugated
Anti-IRX5 Antibody (aa455-483, FITC) LS-C260404
Rabbit Polyclonal (IgG) to Human IRX5
Human, Mouse
Western blot, ELISA
FITC Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human IRX5
Human, Bovine
IHC - Paraffin, ELISA
Unconjugated

Details

Human IRX5
Rabbit
Human, Bovine (tested or 100% immunogen sequence identity)
Monkey, Mouse, Rat, Dog (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • ELISA (1:250000)

Specificity and Use

IRX5 antibody was raised against synthetic peptide, aa351-363 (acetyl) GGNEGSPCPPCPG- LYS corresponding to human Irx2a (KLH). Percent identity by BLAST analysis: Human, Bovine (100%); Gibbon, Monkey, Mouse, Rat, Elephant, Panda, Dog (92%); Gorilla, Marmoset, Hamster (85%).
aa351-363
Recognizes human Irx2a, (Iroquois family), a homeodomain transcription factor. Species cross-reactivity: rodent.
Immunohistochemistry: LS-B3078 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3078 was determined to be 5 ug/ml.

Packaging

PBS, 0.02% sodium azide, glycerol to 40%.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About IRX5

P78411 NM_005853 NP_005844.4

IRX5 Antibody, IRX2A Antibody, Homeodomain protein IRX-2A Antibody, Iroquois homeobox 5 Antibody, Iroquois homeobox protein 5 Antibody, HMMS Antibody, Homeodomain protein IRXB2 Antibody, IRX-2a Antibody, IRXB2 Antibody

Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells. Involved in craniofacial and gonadal development.

Immunohistochemistry

Immunohistochemistry
Anti-IRX5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3078 concentration 5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-IRX5 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3078 concentration 5 ug/ml.

Requested From: United States
Date Requested: 12/6/2016

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