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Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.
Gene Name: | IQ motif containing GTPase activating protein 1 |
Family/Subfamily: | Protease Regulatory , not assigned-Protease Regulatory |
Synonyms: | IQGAP1, HUMORFA01, p195, KIAA0051, RasGAP-like with IQ motifs, SAR1 |
Target Sequences: | NM_003870 NP_003861.1 P46940 |
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