Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IPO8 Antibody, Imp8 Antibody, Importin 8 Antibody, Importin-8 Antibody, Ran-binding protein 8 Antibody, RAN binding protein 8 Antibody, RANBP8 Antibody
Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism.
IPO8 Antibody (N-term) IHC of formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This demonstrates the use of the IPO8 Antibody (N-term) for immunohistochemistry.
IPO8 Antibody (N-term)Western blot of HeLa cell line lysates (35 ug/lane). This demonstrates the IPO8 antibody detected the IPO8 protein (arrow).
IPO8 Antibody (N-term) flow cytometry of HeLa cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.