Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone PB36] (IgG1) to Human Integrin Alpha 3B/6B
IHC - Frozen, ICC, Western blot
Human Integrin Alpha 3B/6B
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [PB36]
IHC - Frozen (1:50 - 1:100)
Western blot (1:100 - 1:500)
IHC - Paraffin
Specificity and Use
Synthetic peptide corresponding to a 32 amino acid stretch in the cytoplasmic domain of integrin alpha-3B including an appending N-terminal cysteine (CTRYYQIMPKYHAVRIREEERYPPPGSTLPTKK) coupled to keyhole limpet hemocyanin
Recognizes the cytoplasmic domain of integrin subunits alpha-3B and alpha-6B. Reacts with the basement membrane zone and endothelial cells in skin, tubuli in kidney and all vascular and capillary endothelia in brain and heart. A broad species reactivity is expected because of the conserved nature of the epitope.
PBS containing 0.09% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.