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Anti-Insulin Antibody (C-Terminus, clone C7C9) LS-C52270

Catalog Size Price
LS-C52270-200 200 µg Unavailable

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100% Guaranteed
Mouse Monoclonal [clone C7C9] (IgG1) to Human Insulin
Human
IHC, ELISA
Unconjugated

Details

Human Insulin
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [C7C9]
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC
  • ELISA

Specificity and Use

Insulin antibody was raised against purified human insulin.
C-Terminus
C-terminal pentapeptide of insulin beta-chain. MAbs 7F8, D4B8, 3A6 and 8E2 react with different antigenic determinants. Kass MAb 7F8 is 7.5 x 109 M-1 Kass MAb D4B8 is 1.5 x 108 M-1 Kass MAb 3A6 is 8.0 x 108 M-1 Kass MAb 8E2 is 6.0 x 108 M-1 Kass MAb C7C9 is 1.0 x 109 M-1 Kass MAb 7F5 is 1.0 x 109 M-1 These antibodies cross-react with human proinsulin, bovine insulin (30%) and porcine insulin. No cross-reaction with free C-peptide.

Packaging

PBS, pH 7.4, 0.1 % sodium azide.
+4°C, avoid freezing.
For research use only.

About Insulin

P01308 NM_000207 NP_000198.1

INS Antibody, IRDN Antibody, IDDM2 Antibody, Preproinsulin Antibody, ILPR Antibody, Insulin Antibody, MODY10 Antibody, Proinsulin Antibody

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified.

Requested From: 
Date Requested: 8/22/2017

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