LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
Insulin Antibody (C‑Terminus, clone C7C9) LS‑C52270
Antibody
Insulin antibody LS-C52270 is an unconjugated mouse monoclonal antibody to human Insulin. Validated for ELISA and IHC.
Catalog
Size
Price
LS-C52270-200
200 µg
Unavailable

Popular Insulin Products

Anti-Insulin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2407 concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, ELISA
Anti-Insulin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2526 dilution 1:100.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Flow Cytometry
Anti-Insulin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3297 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, ELISA
Anti-Insulin antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5754 concentration 10 ug/ml.
Species: Rat, Human, Mouse, Bovine, Pig
Applications: IHC, IHC - Paraffin, IHC - Frozen, ELISA
Antibody
Species: Human, Bovine, Pig
Applications: ELISA

Product Description

Insulin antibody LS-C52270 is an unconjugated mouse monoclonal antibody to human Insulin. Validated for ELISA and IHC.
About Insulin
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. P01308 NM_000207 NP_000198.1

INS Antibody, IRDN Antibody, IDDM2 Antibody, Preproinsulin Antibody, ILPR Antibody, Insulin Antibody, MODY10 Antibody, Proinsulin Antibody


Specifications

Target
Human Insulin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [C7C9]
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Insulin antibody was raised against purified human insulin.
Epitope
C-Terminus
Specificity
C-terminal pentapeptide of insulin beta-chain. MAbs 7F8, D4B8, 3A6 and 8E2 react with different antigenic determinants. Kass MAb 7F8 is 7.5 x 109 M-1 Kass MAb D4B8 is 1.5 x 108 M-1 Kass MAb 3A6 is 8.0 x 108 M-1 Kass MAb 8E2 is 6.0 x 108 M-1 Kass MAb C7C9 is 1.0 x 109 M-1 Kass MAb 7F5 is 1.0 x 109 M-1 These antibodies cross-react with human proinsulin, bovine insulin (30%) and porcine insulin. No cross-reaction with free C-peptide.
Presentation
PBS, pH 7.4, 0.1 % sodium azide.
Storage
4°C, avoid freezing.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Requested From: 
Date Requested: 6/22/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number