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Anti-INSIG1 Antibody (C-Terminus) LS-C110485

Ordering

Wt. Vol. Conc. Price
50 µg - - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular INSIG1 Antibodies

Anti-INSIG1 Antibody (aa1-100) IHC-plus™ LS-B2420
Rabbit Polyclonal to Human INSIG1
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-INSIG1 Antibody (aa63-112) IHC-plus™ LS-B6815
Rabbit Polyclonal to Human INSIG1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Goat, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-INSIG1 Antibody (N-Terminus, AP) LS-C278343
Rabbit Polyclonal (IgG) to Human INSIG1
Human
Western blot, ELISA
AP Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human INSIG1
Human
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human INSIG1
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

INSIG1 antibody was raised against synthetic peptide from C-Terminus of human INSIG1 (A4D2M9, NP_938150). Percent identity by BLAST analysis: Human, Gorilla (100%); Marmoset (85%); Arabidopsis (81%).
LS-E14603 - Lyophilized - 100 µg - $145.00
C-Terminus
Human INSIG1
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About INSIG1

O15503 NM_005542 NP_005533.2

INSIG1 Antibody, Cl-6 Antibody, CL6 Antibody, INSIG-1 Antibody, Insulin induced gene 1 Antibody, Insulin-induced gene 1 protein Antibody, INSIG-1 membrane protein Antibody

Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78.

Western blot

Western blot
INSIG1 antibody LS-C110485 Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/5/2016

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