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Anti-INSIG1 Antibody (aa71-120) LS-C101825

Catalog Size Price
LS-C101825-50 50 µg Unavailable

Related Products

31 INSIG1 Antibodies

Most Popular INSIG1 Antibodies

Anti-INSIG1 Antibody (aa1-100) IHC-plus™ LS-B2420
Rabbit Polyclonal to Human INSIG1
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Immunohistochemistry Image
Anti-INSIG1 Antibody (aa63-112) IHC-plus™ LS-B6815
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Immunohistochemistry Image
Anti-INSIG1 Antibody (aa36-63) LS-C165254
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Anti-INSIG1 Antibody (N-Terminus) LS-C327623
Rabbit Polyclonal (IgG) to Human INSIG1
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Anti-INSIG1 Antibody LS-C411032
Rabbit Polyclonal (IgG) to Human INSIG1
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100% Guaranteed
Rabbit Polyclonal (IgG) to Human INSIG1
Human, Mouse, Rat, Bovine, Goat, Hamster, Horse, Pig, Rabbit, Sheep, Xenopus
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human INSIG1
Rabbit
Human, Mouse, Rat, Bovine, Goat, Hamster, Horse, Pig, Rabbit, Sheep, Xenopus (tested or 100% immunogen sequence identity)
Monkey, Bat, Dog, Guinea pig, Chicken (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

  • IHC - Paraffin

Specificity and Use

INSIG1 antibody was raised against synthetic peptide located between aa71-120 of human INSIG2 (Q9Y5U4, NP_057217). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Galago, Mouse, Rat, Sheep, Goat, Hamster, Elephant, Bovine, Rabbit, Horse, Pig, Opossum, Xenopus (100%); Marmoset, Dog, Bat, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Lizard (93%); Seabass, Salmon, Smelt, Stickleback, Zebrafish (86%).
LS-E14606 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C101825. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa71-120
Human INSIG1
Western Blot: Suggested dilution at 1µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:1562500.

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About INSIG1

O15503 NM_005542 NP_005533.2

INSIG1 Antibody, Cl-6 Antibody, CL6 Antibody, INSIG-1 Antibody, Insulin induced gene 1 Antibody, Insulin-induced gene 1 protein Antibody, INSIG-1 membrane protein Antibody

Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78.

Western blot

Western blot
INSIG1 antibody LS-C101825 Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 10/19/2017

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