Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1.B.408] (IgG1) to Influenza Virus Influenza A Virus H1
Mouse Monoclonal [clone 58AB7-19-18] (IgG1) to Influenza Virus Influenza A Virus H1
Influenza Virus Influenza A Virus H1
Influenza Virus (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [58AB7-19-18]
Immunofluorescence (1:25 - 1:100)
Specificity and Use
Specific for the Influenza A H1 antigen Recognizes most H1N1 strains isolated in California since 1986, including A/Taiwan/1/86 and A/USSR/90/77. Some cross reactivity has been observed with A/Texas/36/91 and the New Caledonia strain seen after 1998. Does not recognize the following H3N2 strains: A/Wuhan/396/95, A/Johannesburg/33/94, A/Shandung/93, A/Shanghai/16/89, all CA strains isolated from 1986 to the present.
PBS, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.
About Influenza A Virus H1
Influenza hemagglutinin (HA) is a glycoprotein found on the surface of the influenza viruses. It is responsible for binding the virus to cells with sialic acid on the membranes, such as cells in the upper respiratory tract or erythrocytes. It is also responsible for the fusion of the viral envelope with the endosome membrane, after the pH has been reduced. The name "hemagglutinin" comes from the protein's ability to cause red blood cells (erythrocytes) to clump together ("agglutinate") in vitro.