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Anti-IL2RB / CD122 Antibody (Low Endotoxin) LS-C44744

Ordering

Wt. Vol. Conc. Price
500 µg - 1 mg/ml $475
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular IL2RB / CD122 Antibodies

Anti-IL2RB / CD122 Antibody (clone DU-2) LS-C35818
Mouse Monoclonal [clone DU-2] (IgG2a,k) to Human IL2RB / CD122
Human
Flow Cytometry
Unconjugated
Anti-IL2RB / CD122 Antibody (clone MIK-beta 1) LS-C44098
Mouse Monoclonal [clone MIK-beta 1] (IgG2a) to Human IL2RB / CD122
Human
Flow Cytometry
Unconjugated
Anti-IL2RB / CD122 Antibody (aa27-240) LS-C294883
Rabbit Polyclonal (IgG) to Mouse IL2RB / CD122
Mouse
Western blot, ELISA
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal (IgG2b) to Mouse IL2RB / CD122
Mouse
Immunoprecipitation, Flow Cytometry, Functional Assay (applications tested for the base form of this product only)
Unconjugated, Low Endotoxin

Details

Mouse IL2RB / CD122
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Unconjugated
Protein G purified
Low Endotoxin. Also available Unmodified.

Applications

  • Immunoprecipitation
  • Flow Cytometry (1:10 - 1:50)
  • Functional Assay
  • (applications tested for the base form of this product only)

Specificity and Use

IL2RB / CD122 antibody was raised against cells from murine IL-2RB + transformant TART-mBeta.
Recognizes the murine CD122 cell surface glycoprotein, a 75-85kD molecule also known as interleukin-2 receptor (IL-2R) beta chain. In mouse, CD122 is primarily expressed on natural killer (NK) cells and at lower levels on lymphocyte subsets, monocytes and macrophages. CD122 can associate with the IL-2R alpha chain (CD25) and CD132 to form a functional high affinity receptor complex that binds IL-2. CD132/CD122 heterodimers can also be formed which bind IL-2 with intermediate affinity. IL-2 binding to the IL-2R is important in the generation and differentiation of T lymphocytes and NK cells. Clone TM-beta 1 is reported to block IL-2 high affinity binding to the IL-2R beta receptor. XXX recommend the use of For this purpose.
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4.
For research use only.

About IL2RB / CD122

P14784 NM_000878 NP_000869.1

IL2RB Antibody, CD122 Antibody, CD122 antigen Antibody, IL-2 receptor subunit beta Antibody, IL15RB Antibody, Interleukin 15 receptor, beta Antibody, p70-75 Antibody, IL-2R subunit beta Antibody, IL-2RB Antibody, Interleukin 2 receptor, beta Antibody

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer.

Requested From: United States
Date Requested: 12/4/2016

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