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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL23R Antibody (aa439‑455) LS‑C724 Best Seller
IL23R antibody LS-C724 is an unconjugated rabbit polyclonal antibody to IL23R from human and mouse. Validated for Flow and WB.
Catalog
Size
Price
LS-C724-200
200 µl (0.5 mg/ml)
Unavailable

Popular IL23R Products

Western blot shows lysates of K562 human chronic myelogenous leukemia cell line. PVDF membrane was probed with 2 ug/mL of LS-C37068 followed by HRP conjugated Anti Mouse IgG Secondary Antibody. A specific band was detected for IL 23 R at approximately 58 kD (as indicated). This experiment was conducted under non reducing conditions.
Species: Human
Applications: Western blot, ELISA
Flow Cytometry results: K562 cells were stained with LS-C37069 (filled histogram), or with isotype control (open histogram). This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry
Immunohistochemistry of paraffin-embeddedi mouse spleen stained with Goat anti-human IL-23 Receptor
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemistry of paraffin-embedded human kidney using IL23R antibody at dilution of 1:200 (x400 lens).
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot

Product Description

IL23R antibody LS-C724 is an unconjugated rabbit polyclonal antibody to IL23R from human and mouse. Validated for Flow and WB.
About IL23R
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Q5VWK5 NM_144701 NP_653302.2

IL23R Antibody, IL-23 receptor Antibody, Interleukin 23 receptor Antibody, IBD17 Antibody, IL-23R Antibody, Interleukin-23 receptor Antibody


Specifications

Target
Human IL23R
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (1:500)
  • Flow Cytometry
Immunogen
IL23R antibody was raised against a synthetic peptide corresponding to amino acids 439-455 (EIFIPEHKPTDYKKENT) of human IL-23R was used as immunogen, Genbank no NP_653302. Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%); Gibbon (88%).
Epitope
aa439-455
Specificity
A synthetic peptide corresponding to amino acids 439-455 (EIFIPEHKPTDYKKENT) of human IL-23 receptor was used as immunogen, Genbank no NP_653302.
Presentation
PBS, 0.05% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of IL-23R in (A) Jurkat and (B) NIH3T3 cell lysate using antibody at 0.5 ug/ml.
Western blot of IL-23R in (A) Jurkat and (B) NIH3T3 cell lysate using antibody at 0.5 ug/ml.

Western blot

Western blot of IL-23R in (A) Jurkat and (B) NIH3T3 cell lysate using antibody at 0.5 ug/ml.
Western blot of IL-23R in (A) Jurkat and (B) NIH3T3 cell lysate using antibody at 0.5 ug/ml.

Western blot

Western blot of IL-23R in (A) Jurkat and (B) NIH3T3 cell lysate using antibody at 0.5 ug/ml.
Western blot of IL-23R in (A) Jurkat and (B) NIH3T3 cell lysate using antibody at 0.5 ug/ml.

Western blot

Western blot of IL-23R in (A) Jurkat and (B) NIH3T3 cell lysate using antibody at 0.5 ug/ml.
Western blot of IL-23R in (A) Jurkat and (B) NIH3T3 cell lysate using antibody at 0.5 ug/ml.


Requested From: 
Date Requested: 6/23/2018

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