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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL17A Antibody (clone TC11‑8H4) LS‑C149567
IL17A antibody LS-C149567 is an unconjugated rat monoclonal antibody to mouse IL17A. Validated for Flow.
Antibody
Catalog
Size
Price
LS-C149567-500
500 µg
Unavailable

Popular IL17A Products

Untreated (A) and PMA/ionomycin -stimulated (B) human PBMCs were stained using PE-conjugated mouse anti-human CD3 antibody and APC-conjugated antibody LS-C37030 This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry
Western Blot (reducing) of IL-17 antibody LS-C104427.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: Western blot, ELISA, Neutralization
Anti-IL-17 antibody IHC of human t lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7397 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA, Neutralization
Biotin Rabbit Anti-Rat IL-17A Antibody - Western Blot. Western Blot showing detection of Rat IL-17A. 50 ng of Rat IL-17A (Lane 1) was run on a 4-20% gel and transferred to 0.45 micron nitrocellulose. After blocking with 5% Blotto (B501-0500) 30 min at 20°C, Anti-Rat IL-17A (RABBIT) Antibody Biotin Conjugated LS-C154151 secondary antibody was used at 1:5000 in Blocking Buffer for Fluorescent Western Blot (p/n MB-070). HRP Streptavidin (p/n S000-03) was used at 1:40000 in MB-070 for 30 min at 20°C and imaged using the Bio-Rad VersaDoc 4000 MP. Arrow indicates correct 15 kD molecular weight position expected for Rat IL-17A. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Rat, Mouse
Applications: IHC, Western blot, ELISA
Anti-IL-17 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8323 dilution 5-10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

IL17A antibody LS-C149567 is an unconjugated rat monoclonal antibody to mouse IL17A. Validated for Flow.
About IL17A
IL17A is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. Q16552 NM_002190 NP_002181.1

IL17A Antibody, CTLA-8 Antibody, CTLA8 Antibody, Interleukin-17A Antibody, Interleukin 17A Antibody, IL-17 Antibody, IL-17A Antibody, IL17 Antibody


Specifications

Target
Mouse IL17A
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [TC11-8H4]
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • Flow Cytometry
Immunogen
IL17A antibody was raised against e. coli-expressed recombinant mouse IL-17
Presentation
Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/19/2018

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