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Anti-IL17 Antibody (clone TC11-18H10) IHC-plus™ LS-B4912

Note: This antibody replaces LS-C41753
Catalog Size Price
LS-B4912-100 100 µg (0.5 mg/ml) Unavailable

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36 IL17 Antibodies

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Anti-IL17 Antibody (Biotin) LS-C41752
Rat Monoclonal (IgG1) to Mouse IL17
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Anti-IL17 Antibody LS-C96110
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Anti-IL17 Antibody (clone TC11-18H10) IHC-plus™ LS-B4912
Rat Monoclonal [clone TC11-18H10] (IgG1) to Mouse IL17
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IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image
Anti-IL17 Antibody (aa25-168) LS-C294849
Rabbit Polyclonal (IgG) to Chicken IL17
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Western blot Image
Anti-IL17 Antibody (aa1-155, FITC) LS-C305059
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Western blot Image

100% Guaranteed
Rat Monoclonal [clone TC11-18H10] (IgG1) to Mouse IL17
Mouse
IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Unconjugated

Details

Mouse IL17
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [TC11-18H10]
Unconjugated
Purified from ascites.
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot
  • Flow Cytometry
  • ELISA

Specificity and Use

IL17 antibody was raised against e. coli-expressed, recombinant mouse IL-17A
Recognizes mouse Interleukin 17, a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.
ELISA: This antibody can be used in a sandwich ELISA with LS-C41752 as a detection antibody.

Packaging

Borate buffered saline.
Aliquot and store at -20°C. Minimize freezing and thawing.
For research use only.

About IL17

Interleukin 17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation, similar to Interferon gamma. IL-17 is produced by T-helper cells and is induced by IL–23 which results in destructive tissue damage in delayed-type reactions.

Immunohistochemistry

Immunohistochemistry
Anti-IL-17 antibody IHC of mouse spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4912 concentration 10 ug/ml.

Requested From: 
Date Requested: 12/11/2017

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